Monticello is a town in and the county seat of Lawrence County, Mississippi, United States. The population was 1,571 at the 2010 census.
According to the United States Census Bureau, the town has a total area of 3.3 square miles (8.5 km²), of which 3.2 square miles (8.3 km²) is land and 0.1 square miles (0.26 km²) (2.69%) is water.
As of the census of 2000, there were 1,726 people, 690 households, and 451 families residing in the town. The population density was 530.4 people per square mile (205.1/km²). There were 754 housing units at an average density of 231.7 per square mile (89.6/km²). The racial makeup of the town was 64.19% White, 34.18% African American, 0.98% Asian, and 0.64% from two or more races. Hispanic or Latino of any race were 0.06% of the population.
There were 690 households out of which 32.2% had children under the age of 18 living with them, 42.9% were married couples living together, 19.0% had a female householder with no husband present, and 34.6% were non-families. 32.9% of all households were made up of individuals and 15.4% had someone living alone who was 65 years of age or older. The average household size was 2.37 and the average family size was 3.01.
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